• Atraumatic (pencil-point) versus conventional needles for lumbar puncture: A clinical practice guideline 

      Rochwerg, B.; Almenawer, S. A.; Siemieniuk, Reed Alexander C.; Vandvik, Per Olav; Agoritsas, Thomas; Lytvyn, Lyubov; Alhazzani, Waleed; Archambault, Patrick; D'Aragon, Frédérick; Farhoumand, Pauline Darbellay; Guyatt, Gordon Henry; Laake, Jon Henrik; Beltrán-Arroyave, Claudia; McCredie, Victoria; Price, Amy; Chabot, Christian; Zervakis, Tracy; Badhiwala, Jetan; St-Onge, Maude; Szczeklik, Wojciech; Møller, Morten Hylander; Lamontagne, François (Peer reviewed; Journal article, 2018)
      Is the needle tip configuration important when performing a lumbar puncture for any indication? A systematic review published in the Lancet in December 2017 suggests that it is. The review found that using atraumatic ...
    • Corticosteroid therapy for sepsis: A clinical practice guideline 

      Lamontagne, François; Rochwerg, Bram; Lytvyn, Lyubov; Guyatt, Gordon H.; Møller, Morten Hylander; Annane, Djillali; Kho, Michelle E.; Adhikari, Neill K. J.; MacHado, Flavia; Vandvik, Per Olav; Dodek, Peter; Leboeuf, Rebecca; Briel, Matthias; Hashmi, Madiha; Camsooksai, Julie; Shankar-Hari, Manu; Baraki, Mahder Kinfe; Fugate, Karie; Chua, Shunjie; Marti, Christophe; Cohen, DIan; Botton, Edouard; Agoritsas, Thomas; Siemieniuk, Reed Alexander C. (Peer reviewed; Journal article, 2019)
      Do corticosteroids reduce death or improve recovery in people with sepsis or septic shock? Our panel make a weak recommendation to give corticosteroids to people with all types and severity of sepsis, based on new evidence. ...
    • Patent foramen ovale closure, antiplatelet therapy or anticoagulation in patients with patent foramen ovale and cryptogenic stroke: a systematic review and network meta-analysis incorporating complementary external evidence 

      Mir, Hassan; Siemieniuk, Reed Alexander C.; Ge, Long Cruz; Foroutan, Farid; Fralick, Michael; Syed, Talha; Lopes, Luciane Cruz; Kuijpers, Ton; Mas, Jean-Louis; Vandvik, Per Olav; Agoritsas, Thomas; Guyatt, Gordon H (Journal article; Peer reviewed, 2018)
      OBJECTIVE: To examine the relative impact of three management options in patients aged <60 years with cryptogenic stroke and a patent foramen ovale (PFO): PFO closure plus antiplatelet therapy, antiplatelet therapy alone ...